Raymond N DuBois Selected Research

Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)

12/2021	Cyclooxygenases and Prostaglandins in Tumor Immunology and Microenvironment of Gastrointestinal Cancer.
12/2015	Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.
11/2013	An inflammatory mediator, prostaglandin E2, in colorectal cancer.
4/2010	Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization.
8/2008	Pro-inflammatory prostaglandins and progression of colorectal cancer.
3/2007	Inflammatory mediators and nuclear receptor signaling in colorectal cancer.
2/2006	Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer.
5/2005	The role of prostaglandins and other eicosanoids in the gastrointestinal tract.
4/2005	COX-2: a molecular target for colorectal cancer prevention.
1/2005	Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer.

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Raymond N DuBois Research Topics

Disease

62	Neoplasms (Cancer) 01/2022 - 01/2002
38	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 08/2002
17	Inflammation (Inflammations) 01/2022 - 01/2002
13	Adenoma (Adenomas) 12/2014 - 03/2004
11	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2005
11	Carcinogenesis 10/2014 - 08/2002
7	Carcinoma (Carcinomatosis) 12/2014 - 06/2002
6	Obesity 01/2019 - 12/2004
5	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2022 - 05/2004
5	Colonic Neoplasms (Colon Cancer) 08/2011 - 06/2003
4	Lung Neoplasms (Lung Cancer) 01/2013 - 05/2003
3	Polyps 12/2015 - 03/2004
3	Hypoxia (Hypoxemia) 12/2013 - 02/2003
3	Breast Neoplasms (Breast Cancer) 06/2013 - 05/2004
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2013 - 06/2004
2	Colitis 10/2014 - 05/2014
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2014 - 08/2008
2	Pathologic Processes 09/2010 - 05/2005
2	Intestinal Polyps 10/2007 - 03/2004
2	Prostatic Neoplasms (Prostate Cancer) 06/2006 - 03/2006
2	Ovarian Neoplasms (Ovarian Cancer) 05/2005 - 03/2003
1	Disease Progression 06/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2013
1	Leukemia 12/2007
1	Intestinal Neoplasms (Intestinal Cancer) 10/2007
1	Metabolic Diseases (Metabolic Disease) 12/2006

Drug/Important Bio-Agent (IBA)

24	ProstaglandinsIBA 12/2021 - 05/2003
20	Dinoprostone (PGE2)FDA Link 01/2022 - 09/2003
16	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2014 - 01/2003
14	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 12/2021 - 05/2003
13	Prostaglandins EIBA 01/2012 - 09/2004
11	EnzymesIBA 04/2010 - 01/2002
10	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2022 - 05/2003
9	PPAR deltaIBA 01/2019 - 06/2002
7	LipidsIBA 12/2021 - 05/2004
7	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2019 - 06/2002
6	LigandsIBA 01/2019 - 06/2003
6	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 12/2014 - 03/2002
6	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2014 - 12/2004
5	Celecoxib (Celebrex)FDA Link 12/2015 - 06/2004
5	ErbB Receptors (EGF Receptor)IBA 10/2007 - 01/2005
4	Pharmaceutical PreparationsIBA 12/2021 - 03/2003
4	Biomarkers (Surrogate Marker)IBA 12/2013 - 08/2002
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2007 - 02/2003
3	ChemokinesIBA 01/2022 - 05/2014
3	CytokinesIBA 01/2022 - 05/2014
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 08/2011
3	Dietary Fats (Dietary Fat)IBA 01/2019 - 11/2013
3	Protein Isoforms (Isoforms)IBA 03/2010 - 03/2003
3	15-hydroxyprostaglandin dehydrogenaseIBA 11/2008 - 02/2005
3	GW 501516IBA 12/2006 - 03/2004
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 10/2014
2	Biological ProductsIBA 11/2013 - 01/2005
2	Hormones (Hormone)IBA 04/2012 - 02/2003
2	Antineoplastic Agents (Antineoplastics)IBA 09/2010 - 05/2005
2	Proteins (Proteins, Gene)FDA Link 01/2010 - 01/2005
2	EicosanoidsIBA 01/2007 - 05/2005
2	CD55 Antigens (Decay Accelerating Factor)IBA 02/2006 - 01/2005
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2005 - 01/2004
2	Cyclooxygenase 1IBA 05/2005 - 03/2003
2	PPAR gammaIBA 06/2003 - 06/2002
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2020
1	Early Growth Response Protein 1IBA 01/2016
1	Factor XII (Hageman Factor)IBA 01/2016
1	4- (4- cyano- 2- (2- (4- fluoronaphthalen- 1- yl)propionylamino)phenyl)butyric acidIBA 12/2015
1	Cytotoxins (Cytolysins)IBA 12/2015
1	Protein Kinases (Protein Kinase)IBA 12/2015
1	CG100649IBA 12/2014
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 12/2013
1	FatsIBA 11/2013
1	Arachidonic Acid (Vitamin F)IBA 11/2013
1	7- hydroxy- 5,11- dioxotetranorprostane- 1,16- dioic acidIBA 06/2013
1	Topotecan (Hycamtin)FDA LinkGeneric 02/2013
1	prostaglandin E3 (PGE3)IBA 01/2013
1	Tissue ExtractsIBA 01/2013
1	Eicosapentaenoic AcidIBA 01/2013
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2013
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2013
1	Angiopoietin-Like Protein 4IBA 11/2011
1	Recombinant ProteinsIBA 11/2011
1	Adenosine Triphosphate (ATP)IBA 08/2011
1	Prostaglandin-E SynthasesIBA 04/2010
1	Prostaglandin H2 (PGH(2))IBA 03/2010
1	Messenger RNA (mRNA)IBA 01/2010
1	PPAR-betaIBA 12/2008
1	Histone Deacetylase 2IBA 11/2008
1	CannabinoidsIBA 08/2008
1	EndocannabinoidsIBA 08/2008
1	SurvivinIBA 08/2008
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 08/2008
1	Histone Deacetylase InhibitorsIBA 07/2008
1	A-Form DNA (A-DNA)IBA 07/2008
1	Multidrug Resistance-Associated ProteinsIBA 07/2008
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2007

Therapy/Procedure

6	Therapeutics 01/2016 - 03/2002
5	Chemoprevention 03/2021 - 08/2002
2	Immunotherapy 12/2021 - 01/2016
1	Injections 01/2020
1	Microspheres (Microsphere) 12/2015